Dynamic culture improves cell reprogramming efficiency
نویسندگان
چکیده
منابع مشابه
Dynamical approximation of a reprogramming cell culture
Cellular reprogramming is a process by which differentiated cells such as fibroblasts are converted into pluripotent cells that possess many characteristics of embryonic stem cells. Induced pluripotent cells, like naturally-occurring stem cells, can become any of the endoderm, mesoderm, or ectoderm-derived tissue types (Figure 1). One open problem in this area concerns how some cells are more r...
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Embryonic stem (ES) cells derived from the inner cell mass (ICM) of blastocysts are characterised by their ability to self-renew and their potential to differentiate into many different cell types. Recent studies have shown that zinc finger proteins are crucial for maintaining pluripotent ES cells. Mouse zinc finger protein 322a (Zfp322a) is expressed in the ICM of early mouse embryos. However,...
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It is important to quantify the distribution of behavior amongst a population of individual cells to reach a more complete quantitative understanding of cellular processes. Improved high-throughput analysis of single cell behavior requires uniform conditions for individual cells with controllable cell-cell interactions, including diffusible and contact elements. Uniform cell arrays for static c...
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ژورنال
عنوان ژورنال: Biomaterials
سال: 2016
ISSN: 0142-9612
DOI: 10.1016/j.biomaterials.2016.03.033